[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"$fLVfcQWETahmxwYGh5VnGGDkNlYYi0Kh5koN7SWJU6lg":3},{"answer":4,"createTime":5,"id":6,"options":7,"origin":13,"question":20,"related":21,"source":25,"type":26},[],"2025-05-19 20:14:35",189115735,[8,9,10,11,12],"普伐他汀","阿托伐他汀","瑞舒伐他汀","洛伐他汀","氟伐他汀",{"count":14,"courseId":15,"courseImg":16,"courseName":17,"workId":18,"workName":19},21,"74386828e19f4b12dcc4a80308d72793","https:\u002F\u002Ftihai-oss-cloud.itihey.com\u002Fimg\u002F25b30343053994e8940089572d36015b.jpg","药理学","work_42822553","第二十章 调血脂药与抗动脉粥样硬化药","经体内代谢才具有药理活性的他汀类药物是",[22,27,32,42,52,62,68,73,78,87],{"answer":23,"createTime":5,"id":6,"options":24,"question":20,"source":25,"type":26},[],[8,9,10,11,12],"v1",0,{"answer":28,"createTime":5,"id":29,"options":30,"question":31,"source":25,"type":26},[],189115738,[8,9,10,11,12],"口服后几乎能完全吸收的他汀类药物是",{"answer":33,"createTime":5,"id":34,"options":35,"question":41,"source":25,"type":26},[],189115740,[36,37,38,39,40],"肾脏","胆汁","唾液","汗液","乳汁","他汀类药物的主要排泄途径是",{"answer":43,"createTime":5,"id":44,"options":45,"question":51,"source":25,"type":26},[],189115742,[46,47,48,49,50],"激活HMG-CoA还原酶","使HMG-CoA还原酶恢复活性","诱导HMG-CoA还原酶活性","使HMG-CoA还原酶水解增加","抑制HMG-CoA还原酶活性","他汀类药物的作用机制是",{"answer":53,"createTime":5,"id":54,"options":55,"question":61,"source":25,"type":26},[],189115744,[56,57,58,59,60],"胃肠道反应","头痛","皮肤潮红","横纹肌溶解症","转氨酶升高","他汀类药物最严重的不良反应是",{"answer":63,"createTime":64,"id":65,"options":66,"question":67,"source":25,"type":26},[],"2025-05-19 20:14:36",189115746,[8,11,10,9,12],"第一个用于临床的HMG-CoA还原酶抑制药是",{"answer":69,"createTime":64,"id":70,"options":71,"question":72,"source":25,"type":26},[],189115748,[8,11,12,9,10],"与其他药物相互作用最少且引起肌病概率最低的药物是",{"answer":74,"createTime":64,"id":75,"options":76,"question":77,"source":25,"type":26},[],189115750,[9,10,8,12,11],"第一个人工合成的他汀类药物是",{"answer":79,"createTime":64,"id":80,"options":81,"question":86,"source":25,"type":26},[],189115752,[11,82,83,84,85],"依洛尤单抗","依折麦布","非诺贝特","普罗布考","通过降低胆固醇吸收发挥调血脂的药物是",{"answer":88,"createTime":64,"id":89,"options":90,"question":91,"source":25,"type":26},[],189115754,[82,84,11,83,85],"通过激活PPAR&alpha;发挥调血脂的药物是"]